Las Vegas, NV · Mia LoPreiato, NP · Biote-Certified
Hormone Pellet Therapy for Men & Women
Bioidentical hormone pellets, inserted in a brief in-office procedure, releasing steadily for months at a time — no daily dosing, no weekly injections. Biote-certified, LegitScript-certified, Summerlin.
Hormone pellets are small, custom-compounded implants — roughly the size of a grain of rice — placed subcutaneously in the upper buttock during a brief in-office procedure. Once placed, a pellet doesn't release on a fixed schedule. It releases in response to your body's demand: as blood flow increases during exercise or physical exertion, absorption increases proportionally; at rest, it slows.
Pellet-delivered hormones bypass hepatic first-pass metabolism entirely, absorbing directly into the bloodstream rather than passing through the liver first, as oral hormone therapy does. The result is a stable, sustained baseline with no supraphysiologic spikes and no troughs before the next dose — which is why patients frequently describe feeling "normal again" rather than cycling between feeling well and feeling depleted.
What affects absorption: Pellet clearance rate is individual. Higher activity levels, elevated cortisol, and faster baseline metabolism can cause pellets to absorb somewhat faster — accounted for in dosing calculations and tracked at follow-up labs.
Delivery Method Comparison
Pellets vs. Injections, Creams & Oral Therapy
Delivery method dictates how hormones behave in your bloodstream. Oral hormone therapy passes through the liver, altering its molecular structure. Transdermal patches and daily creams bypass the liver but carry absorption variability and a daily transfer risk to partners or children. Weekly injections allow rapid dose adjustment but create a peak-and-trough pattern — levels spike after the shot and decline before the next one.
At a Glance
Pellets
Injections
Creams / Gels
Oral / Patches
Consistent levels
✓ Stable baseline
Peak / trough
Variable
Inconsistent
Bypasses liver
✓ Yes
✓ Yes
✓ Yes
No (oral)
Patient effort
✓ None between visits
Weekly
Daily
Daily / weekly
Transfer risk
✓ None
✓ None
Yes — skin contact
✓ None
Dose adjustment
Next cycle only
✓ Immediate
✓ Immediate
✓ Immediate
Frequency
Every 3–6 months
Weekly
Daily
Daily / weekly
One honest limitation: if a dose adjustment is needed mid-cycle, it can't be made immediately the way it can with injections or creams. This is why precise pre-insertion dosing — based on comprehensive labs — matters, and why an experienced, Biote-certified provider is a non-negotiable part of the equation.
Recognizing Hormone Decline
The Symptoms That Bring Patients In
Fatigue, brain fog, weight gain that resists diet and exercise, low libido, disrupted sleep, mood changes — these are frequently dismissed as normal aging when they're often measurable, treatable hormonal decline. For the full symptom picture in men and women, these guides cover it in depth:
Women — Candidacy is based on lab results and symptoms, not an age cutoff. Pellets typically combine estradiol and testosterone, with oral progesterone prescribed alongside for women with an intact uterus. Reinsertion is typically every 3–4 months.
Men — Testosterone pellets address confirmed hypogonadism with steady-state delivery instead of the weekly peak-and-crash of injections. Reinsertion is typically every 4–6 months.
Not all hormone pellets are equivalent. The pellets used at Body Balance Medical are compounded by FDA-registered, Biote-partnered pharmacies from bioidentical hormones — most commonly diosgenin from wild yam or soy, processed into the exact molecular structure of human testosterone or estradiol. Every pellet is tested for potency and sterility before release.
Biote certification means Mia has completed structured training in the Biote Method — dosing algorithms built from an evidence base of millions of insertions, insertion technique, lab interpretation, and ongoing patient management. It's a meaningfully different standard than pellet therapy offered without a validated protocol behind it.
2.5M+
Biote insertions performed globally
12+
Years of clinical data behind the protocol
5,700+
Biote-certified providers nationwide
<15
Minutes for the in-office insertion
Mia LoPreiato, NP
Biote-Certified · Hormone & Longevity
Every protocol is built from your labs, not a flat-rate chart — the same evidence base behind 2.5 million Biote insertions, applied to your specific dosing.
In-Office Insertion
The Insertion: Step by Step
Most patients are in and out in under 15 minutes total, including setup and aftercare instructions.
1
Positioning & Prep
You'll lie on your side on the treatment table. The upper buttock area is cleaned with an antiseptic solution.
2
Local Anesthetic
A small amount of lidocaine numbs the insertion site — a brief pinch and sting, fully numb within 60 seconds.
3
Insertion via Trocar
A tiny 3mm incision allows the pellets to be guided into the subcutaneous fat layer. Mild pressure, no sharp pain, under two minutes.
4
Closure
Closed with sterile steri-strips — no stitches. A waterproof bandage covers the site.
Follow-Up & Monitoring
Aftercare
Normal activity resumes immediately. For 5–7 days, avoid vigorous lower-body exercise, heavy squats, swimming, or hot tub soaking to let the incision close fully. Mild tenderness or bruising over the next day or two is normal and typically resolves within days.
Lab work is drawn at four weeks post-insertion for women and six weeks for men, confirming your dose landed in the optimal range before the next cycle's calculation.
Investment
Cost
Pellet therapy is priced as a complete package — comprehensive labs, custom-compounded pellets, and the insertion procedure together, not billed as separate line items. HSA and FSA funds are generally accepted; most insurance plans do not cover bioidentical pellet therapy.
For women, estrogen and testosterone pellets typically last three to four months. For men, testosterone pellets generally last four to six months, depending on metabolism and activity level.
The area is fully numbed with lidocaine before the incision. Most patients feel a brief pinch from the numbing injection and mild pressure during placement — far less uncomfortable than most anticipate.
Strictly evidence-based — calculated from your comprehensive lab panel, medical history, age, weight, and symptom severity using the Biote dosing protocol. Not a standard or flat-rate dose. Your dose is recalculated at every reinsertion.
Biote-partnered pharmacies operate under FDA-registered compounding standards, with every pellet tested for potency and sterility. Biote certification means your provider completed specialized training in evidence-based dosing and insertion technique — refined across more than 2.5 million procedures — rather than offering pellet therapy without a validated protocol behind it.
Yes. Testosterone is the most abundant biologically active hormone in the female body. Pellets for women are dosed significantly lower than for men, restoring function without virilizing side effects when properly dosed. See Testosterone for Women for the full picture.
Patient Reviews
What Patients Say
Real Google and Yelp reviews from Body Balance Medical hormone and pellet therapy patients at our Summerlin clinic.
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